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First up, do this:

mknod /dev/usbscanner c 180 48
chmod a+rw /dev/usbscanner
chmod 666 /dev/usbscanner
ln -s /dev/usbscanner /dev/scanner
modprobe scanner vendor=0x04a9 product=0x2206

Then, download some files here:
http://homepage.ntlworld.com/millwardjp/

Also, there's a commercial alternative here:
http://www.hamrick.com/vuescan/vuescan.htm

It just ain't working. I also tested it on Ubuntu to the same result. It's recognized correctly by the system but when trying to scan it makes grinding noises.

Flawlessly as a "plustek"-device.
The ebuild installed is media-gfx/sane-backends-1.0.18-r4

Please follow instructions on downgrading libsane available at https://bugs.launchpad.net/ubuntu/+source/sane-backends/+bug/83957

Ubuntu 8.04 Plugged this scanner in and it just worked.