Howtoforge posted a guide on how to integrate ClamAV (Through mod_clamav) into ProFTPd for Virus Scanning on Ubuntu 10.04

This tutorial explains how you can integrate ClamAV into ProFTPd for virus scanning on an Ubuntu 10.04 system. This is achieved through mod_clamav. In the end, whenever a file gets uploaded through ProFTPd, ClamAV will check the file and delete it if it
is malware.

  How To Integrate ClamAV (Through mod_clamav) Into ProFTPd For Virus Scanning On Ubuntu 10.04